Chondroitin Sulfate A is an acidic mucopolysaccharide found in cartilage, skin, cornea, and umbilical cord. It is composed of alternating N-acetyl galactosamine, D-glucuronic acid, and sulfate residues in equimolar quantities where carbon 4 of the N-acetyl galactosamines is sulfated.Chondroitin appears to play a regulatory role for chondrocytes, neural cells, and some tumor cells. Chondroitin sulfate B is used to study ß peptide (1-42) cytotoxicity.
Characters | Unit | Specification |
---|---|---|
Description | The product occurs as a white to pale yellow-brown powder. It is odourless or has a slight, characteristic odour and taste. It is freely soluble in water, and practically insoluble in ethanol, in acetone and in ether. The pH of a solution of Sodium Chondroitin Sulfate (1 in 100) is between 5.5 and 7.5. It is hygroscopic. | |
Identification: | ||
Hexuronic acid | red to red-purple colour | |
Acrinol reaction | yellow precipitate | |
Qualitative reaction (1) of Sulfate | white precipitate, which does not dissolve upon addition of dil. Nitric acid | |
Qualitative reaction (1) of Sodium salt | yellow colour in flame colouration test | |
Purity: | ||
Clarity & colour of solution | colourless or pale yellow & clear | |
Chloride | % | NMT 0.142 |
Sulfate | % | NMT 0.24 |
Heavy metals (as Pb) | ppm | NMT 20 |
Arsenic | ppm | NMT 2 |
Loss on Drying | % | NMT 10.0 |
Residue on Ignition | % | 23.0 - 31.0 |
Assay: | ||
Nitrogen | % | 2.5 - 3.8 |
Sulfur | % | 5.5- 7.5 |
Storage/Shipping Conditions:
Pack Sizes: 50 gm, 100 gm, 1 Kg