Ophthalmic preservatives, such as Polyquaternium-1 (PQ-1), are critical for the inhibition of growth of microbial contaminants in multi-dose bottles of topical medications.
Characters | Unit | Specification |
---|---|---|
Appearance | Light yellow to Agate crystal powder | |
Odour | Without stimulation | |
Water Solubility | 100 % Soluble | |
Free Amin | % | ≤ 2.0 |
Residue on Ignition | % | ≤ 2.0 |
Heavy Metals | ppm | ≤ 20 |
pH | 6.0 - 9.0 | |
Chloride | % | ≤ 25 |
Solid Content | % | ≥ 95 |
Assay | % | 95 - 100 |
Total Aerobic Bacteria | cfu/g | ≤ 100 |
Fungi/Yeast | cfu/g | ≤ 10 |
Enterobacteria in 1g | Negative | |
Pseudomonas Aeruginosa in 1 g | Negative | |
Staphylococcus Aureus in 1 g | Negative |
Storage/Shipping Conditions:
Pack Sizes: 100 gm