Myristyl-Gamma-Picolinium Chloride
Pharma Grade
CAS #:
2748-88-1
Molecular Formula:
C20H36N.Cl
Synonym:
4-Methyl-1-tetradecylpyridinium Chloride, 1-Tetradecyl-4-picolinium chloride, MPC- Miripirium chloride, Quatresin, Wet- Tone B
Molecular Weight:
326.02 g/mol
Overview
Myristyl-gamma-picolinium chloride (MGP) is a novel constituent of methylprednisolone acetate suspensions used for intra-articular corticosteroid therapy.
| Characters | Unit | Specification |
|---|---|---|
| Appearance | Off white to pale orange, pink solid | |
| Solubility | Soluble in ACN | |
| Identification | By NMR | |
| Identification - IR | Conforms to Structure | |
|
Identification - Chlorides
current USP and supplements <191>
Use 20 mg sample in 2 ml of water USP 40 NF 35 |
Respond to Identification Test for Chloride |
|
| Residue on ignition current USP and supplements <281> USP 40 NF 36 | Conforms | |
| Residual Solvents |
Ethyl Acetate: ≤5000 ppm Acetone: ≤5000 ppm |
|
| Water by KF | % | ≤10.0% |
| Purity by HPLC | % | ≥98% |
| Assay (as - is) | % | 90 - 100% |
|
pH Use 0.1% w/v Solution in WFI |
3.5 - 7.0 | |
| Assay (on anhydrous basis) | % | 98.0 - 102.0% |
| Related substances by HPLC (Total Impurities) | % | ≤1.0% |
| Chloride content (on anhydrous basis) | % | 10.0 - 11.8% |
Storage/Shipping Conditions:
- Store in a tightly closed container.
- Store in a cool, dry, well- ventilated area away from incompatible substances.
Pack Sizes: 25 gm
