Guanidine Hydrochloride is a strong protein denaturant that functions as a chaotropic agent. As a denaturant, it acts to unfold proteins and turn them into their original polypeptide chains. As a chaotropic agent, it breaks down the structure of proteins. Guanidine Hydrochloride is commonly used in the purification of RNA by dissociating the RNA into its nucleic acids and protein forms. At higher concentrations, Guanidine Hydrochloride decreases enzyme activity. It is also used to increase the solubility of hydrophobic molecules.
|260 nm||a.u||0.0300 a.u. maximum|
|275 nm||a.u||0.0300 a.u. maximum|
|230 nm||a.u||0.2000 a.u. maximum|
|Appearance and Color||White / Crystals|
|Identification (IR)||Passes Test|
|Insoluble Matter||%||0.15% maximum|
|Loss on Drying||%||0.5% maximum|
|Residue on Ignition||%||0.05% maximum|
|Solubility (6M)||Passes Test|
|Arsenic (As)||ppm||5 ppm maximum|
|Copper (Cu)||ppm||5 ppm maximum|
|Iron (Fe)||ppm||5 ppm maximum|
|Lead (Pb)||ppm||5 ppm maximum|
Shelf Life/Retest Date: The recommended retest period for GuanidineHydrochloride, CAS number – 50-01-1 is 2 years from the date of manufacture.
Pack Sizes:1 Kg