Macrogol 4000 Powder

USP/NF, EP (Tested for Endotoxin & Microbes)

CAS #:


Molecular Formula:



Polyglycol, Polyethylene oxide

Molecular Weight:

3500 - 4500 g/mol


Polyethylene Glycol 4,000, commonly referred to as PEG 4000, is a polyether compound that is used in a wide variety of fields including pharmaceutical manufacturing as an excipient and active ingredient. Due to its low toxicity it can be used as a lubricating coating for various surfaces in aqueous and non-aqueous environments, a reagent in biochemistry to create very high osmotic pressures, a polar stationary phase for gas chromatography and as a binder.

Characters Unit Specification
Appearance white or almost white solid with a waxy or paraffin-like appearance
Acidity or alkalinity ml 0,1M NaOH max. 0,1
Kinematic viscosity (50% solution with density 1,080g/cm³) mm²/s 102 – 158
Dynamic viscosity (50% solution with density 1,080g/cm³) mPas 110 – 170
Freezing point oC 53 - 59
Hydroxyl value (calculated on 14,0g) 25 - 32
Reducing substances complies
Formaldehyde ppm max. 30
Ethylen oxide ppm max. 1
1,4-Dioxane ppm max. 10
Heavy metals ppm max. 20
Water % max. 2,0
Sulphated ash % max. 0,2
pH value (5% aqu.) 4,5 – 7,5
Average molecular weight % 90,0 – 110,0
g/mol 3600 - 4400
Total aerobic microbial count cfu/g max. 100
Total yeasts and moulds count cfu/g max. 50
E.coli cfu/g absent in 1g
Pseudomonas aeruginosa cfu/g absent in 1g
Staphylococcus aureus cfu/g absent in 1g
Salmonella cfu/g absent in 25g
Bacterial endotoxin I.U./g max. 10
Residual Solvents (Ph. Eur., USP) According to requirements

Shelf Life/Retest Date: Macrogol 4000 powder can be kept for at least 2 years if stored under recommended conditions.

Storage/Shipping Conditions:

  • Store at +15°C to +25°C.
  • Store in cool, dry conditions in well-sealed containers.
  • Protect from humidity and keep away from water.

Pack Sizes: 4 Kg

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