D-(+)-Trehalose Dihydrate

USP,EP,Injectable Grade

CAS #:

6138-23-4

Molecular Formula:

C12H22O11 . 2H2O

Synonym:

α,α-TREHALOSE; α-D-GLUCOPYRANOSYL-α-D-GLUCOPYRANOSIDE

Molecular Weight:

378.33 g/mol

Overview

D-(+)-Trehalose, Dihydrate, is a natural alpha-linked disaccharide that is also referred to as mycose or tremalose. It is found naturally in plants and microorganisms such as grasshoppers, shrimp, butterflies and bees. It is thought to have a use in the treatment for Huntington's and Parkinson's disease as it possibly corrects defects in autophagy seen in these diseases.

Characters Unit Specification
Appearance White microcryst. solid
Solubility Freely soluble in water, slightly soluble in MeOH, practically insoluble in EtOH (96%)
Identity A (EP <2.2.24>) IR
Identity B Violet color develops
Identity C No brown color develops
Appearance of Solution Solution S is clear (EP <2.2.1>) and colorless (EP <2.2.2, Method II>)
pH (EP <2.2.3>) 4.5-6.5
Sp. Rot., [α]D (EP <2.2.7>) o +197-+201° (anhydrous)
Heavy Metals (EP <2.4.8>) ppm ≤ 5
Chlorides (EP <2.4.4>) ppm ≤ 125
Sulfates (EP <2.4.13>) ppm ppm ≤ 200
Soluble Starch (EP) No blue color develops
Water (EP <2.5.12>) % 9-11%
Assay (EP <2.2.29>) % ≥ 99
Impurity A (Glucose) % ≤ 0.5
Impurity B (Oligosaccharides) % ≤ 0.5
Unspecified Impurities
(EP <2.2.29>) % ≤ 0.2 (each)
Total Impurities (EP <2.2.29>) % ≤ 1 (each)
Residual Solvents
MeOH ppm < 3,000
EtOH ppm < 5,000
Methyl Isobutyl Ketone ppm < 5,000
Sulfated Ash (EP <2.4.13>) % ≤ 0.1
Microbiological Specification
Total Aerobic (EP <2.6.12>) CFU/g ≤ 100
E. Coli (EP <2.6.13>) negative
Salmonella (EP <2.6.13>) negative
Mold and Yeast (EP <2.6.12>) CFU/g ≤100
Endotoxin Level (EP <2.6.14>) EU/ mg ≤ 2.5

Shelf Life/Retest Date: The minimal shelf-life of D-(+)-Trehalose Dihydrate CAS 6138-23-4 is 2 years when stored under recommended conditions.

Storage/Shipping Conditions:

  • Keep container tightly closed in a dry and well-ventilated place.
  • Store at room temperature in the original container.
  • Store away from incompatible materials.

Pack Sizes: 5 Kg

Please enter your name.
Please enter your company name.
Please enter your email.
Phone number should be between 7 - 15 digits!
Please enter product name.
Please enter your message.