L-Methionine
EP, USP + LEC + Microbiological requirements
CAS #:
63-68-3
Molecular Formula:
C5H11NO2S
Synonym:
L-2-Amino-4-(methylthio)butyric Acid
Molecular Weight:
149.2 g/mol
Overview
L-Methionine is an amino acid which is typically abbreviated as Met or M. It is classified as nonpolar and considered as an essential amino acid in all metazoan. It is used to prevent liver damage in acetaminophen poisoning.
| Characters | Unit | Specification |
|---|---|---|
| Identity A (EP) | o | Correlates to test |
| Identity B (EP) | Correlates to test | |
| Identity A (USP) | Correlates to test | |
| Appearance of solution (EP) | Correlates to test | |
| Assay (EP) | % | 99.0 - 101.0 |
| Assay (USP) | % | 98.5 - 101.5 |
| pH-value (EP) | 5.5-6.5 | |
| pH-value (USP) | 5.6-6.1 | |
| Specific optical rotation (EP) | o | 22.5 - 24.0 |
| Specific optical rotation (USP) | o | 22.4 - 24.7 |
| Unspecified impurities (EP) | % | ≤ 0.1 |
| Total impurities (EP) | % | ≤ 0.3 |
| Methionine sulfoxide (USP) | % | ≤ 0.1 |
| N-Acetyl-D, L-methionine (USP) | % | ≤ 0.2 |
| Any unspecified impurities (USP) | % | ≤ 0.1 |
| Total unspecified impurities (USP) | % | ≤ 0.30 |
| Chlorides | mg/kg | ≤ 200 |
| Sulphates | mg/kg | ≤ 300 |
| Ammonium | mg/kg | ≤ 200 |
| Iron | mg/kg | ≤ 10 |
| Heavy metals | mg/kg | ≤ 5 |
| Loss on drying (EP) | % | ≤ 0.5 |
| Loss on drying (USP) | % | ≤ 0.3 |
| Residue on Ignition | % | ≤ 0.4 |
| Sulphated ash | % | ≤ 0.1 |
| Bacteria Endotoxins | IU/g | ≤ 5 |
| TAMC | CFU/g | ≤ 50 |
| TYMC | CFU/g | ≤ 10 |
Shelf Life/Retest Date: L-Methionine CAS No - 63-68-3 can be kept for at least 4 years if stored in a cool and dry place.
Storage/Shipping Conditions:
- Keep container tightly closed in a cool, well-ventilated place.
- Storage temperature recommended: < 25°C
Pack Sizes: 4 Kg
